ชื่อเรื่อง : Novel Chromogenic Spray Reagent for Thin-Layer Chromatographic Analysis of Paraquat and Design of an Ultra-Low-Cost Sensor for On-The-Field Detection of Viologens
ผู้แต่ง : Asif M. Pathan, Mohammad A. Baseer, Archana B. Kadam, and Subhash B. Junne
แหล่งที่มา : JPC - Journal of Planar Chromatography - Modern TLC 32 (4) 2019 : 335-338
บทคัดย่อ :
A novel spot test and a novel chromogenic reagent are reported for thin-layer chromatographic detection and identifi cation of the popular but highly toxic herbicide paraquat. Alkaline phenylhydrazine instantly reduces paraquat to an intense purple radical cation. The reaction is sensitive and highly specifi c to viologens, i.e., paraquat and diquat herbicide. Surprisingly, 2,4-dinitrophenylhydrazine does not have reaction in this color test. Reaction of the two drugs containing related functional groups is also studied to check whether these drugs also react similarly. Based on this novel color reaction, a simple, ultra-low-cost fi lter-paper-based sensor is also designed for direct fi eld testing of suspicious forensic samples like vomits and bottle of poison, which are usually found at a crime scene. The possible applications of the reported reaction in the fi eld of organic qualitative analysis, clinical chemistry, and forensic medicine are also discussed.
