Research & Article

Combating Devastating COVID -19 by Drug Repurposing

ชื่อเรื่อง : Combating Devastating COVID -19 by Drug Repurposing

ชื่อผู้แต่ง : Ashish Yashwantrao Pawar

สำนักพิมพ์ : ELSEVIER

เนื้อหาโดยย่อ : Abstract: Despite advances in Drug Discovery, the viral infections always remain the major challenge for the Scientists across the globe. The recent pandemic COVID-19 viral infection has created a disastrous situation all over the world. As no drug is available to treat such life- threatening disease and the mortality rate is significantly increased due to COVID-19; there is an utmost need to cure the infection by Drug Repurposing. Some counties are against the use of these drugs because of adverse effects associated with drug repurposing and lack of statistically significant clinical data but they were found to be effective in some countries to treat affected COVID-19 patients (Off label/ Investigational). The article emphases the possible drug candidates in the treatment of COVID-19 infection. Most of these drugs were found to be effective in in vitro studies. There is a need to reassess the in vitro data and to carry out randomised clinical trials. Further investigations of these drugs are recommended on the priority basis.